pharmaceutical solutions - a science lab

SOLUTIONS

Validation & Verification Services

Strategic Validation & Verification: Engineering Global Compliance Excellence

In highly regulated sectors, validation is a critical driver of operational integrity, patient safety, and product quality. ITS provides a complete, consultancy-led Validation and Verification (V&V) process that bridges the gap between complex digital engineering and stringent international standards. Our approach is built on the principles of agility and scalability, ensuring that systems—from standalone equipment to enterprise-wide digital architectures—are validated with precision and efficiency.

We move beyond traditional "paper-heavy" exercises by integrating digital-first validation strategies that align with GAMP® 5 and ALCOA+ principles. Whether embarking on a greenfield facility or modernising a legacy estate, our global consultancy team delivers the technical rigor required to navigate the complexities of FDA, MHRA, and EMA compliance. By providing a flexible engineering partnership, we ensure your "Digital Thread" remains secure and fully compliant on a global scale.

VALIDATION & VERIFICATION SERVICES

SERVICES INCLUDE, NOT LIMITED TO:

01

Validation Strategy & Master Planning (VMP)

Success in validation begins with a scalable and strategic roadmap. Our consultants develop comprehensive Validation Master Plans (VMPs) that define the scope, responsibilities, and methodologies for the entire project lifecycle. We apply a flexible, risk-based approach to ensure resources are focused on the most critical system functions—those with the highest impact on safety and quality. This strategic planning phase provides a clear, predictable path to compliance, ensuring all stakeholders are aligned before any testing is executed.

02

Requirement Engineering & Risk-Based Specification

A system is only as effective as its definition. Our team specialises in the development of robust User Requirement Specifications (URS), Functional Specifications (FS), and Design Specifications (DS) that serve as the technical foundation for your project. By performing detailed Quality Risk Management (QRM) assessments at this stage, we identify potential failure modes and define precise testing parameters. This agile specification process ensures that your system is validated to meet exact operational needs from day one.

03

Digital Validation Excellence with Kneat

As a Kneat Silver Partner—and the only Silver Partner currently operating in the UK—we provide an exclusive, paperless validation capability. By leveraging the Kneat platform, we transform the validation process into a dynamic, digital workflow:

Real-Time Collaboration: Stakeholders can review and approve protocols simultaneously from any global location.

Reduced Cycle Times: Digital execution eliminates the delays of physical document handling, accelerating time-to-market.

Enhanced Data Integrity: Automated audit trails and electronic signatures ensure your validation data is immutable and fully compliant with global standards.

04

Equipment & Process Qualification (IQ/OQ/PQ)

We deliver a complete suite of qualification services to provide documented evidence that your assets operate consistently and reliably:

Design Qualification (DQ): Verifying that the proposed design of the equipment or system is suitable for the intended purpose and meets all required technical and regulatory specifications.

Installation Qualification (IQ): Verifying that equipment is installed correctly and configured to the manufacturer’s specifications.

Operational Qualification (OQ): Testing the full operating range, including "worst-case" scenarios and failure modes.

Performance Qualification (PQ): Documenting that the process consistently produces products meeting quality requirements under real-world conditions.

05

Data Integrity & ALCOA+ Compliance

In the era of Industry 4.0, data is your most valuable asset. Our consultants integrate Data Integrity audits and remediation strategies into every validation project. We apply ALCOA+ principles (Attributable, Legible, Contemporaneous, Original, and Accurate) to ensure that digital records are trustworthy. We assist in implementing automated audit trails and individual user authentication, ensuring your global data architecture is fully compliant with the most scrutinised areas of life science and nuclear regulation.

06

Managed Validation & Legacy Modernisation

Validation is a continuous journey. We offer flexible Managed Validation Services that include periodic reviews, change management, and "re-Validation" support to maintain your system's validated status. For facilities dealing with obsolescence, our team provides specialised Legacy Remediation, reverse-engineering old logic to bring aging systems up to modern compliance standards. Our agile support models allow you to scale technical validation resources as needed, ensuring your enterprise remains resilient 24/7/365.

Meeting Global Regulatory Standards In Validation & Verification